Large drugmakers with the lowest EV/EBIT

Ranked

48

of 412 large drugmakers we cover

Median

12.4×

Lowest

1.2×

ATNM

Range

1.2× to 140×

#	Company	EV/EBIT	PE	Operating margin	Market cap
1	ATNMActinium Pharmaceuticals	1.2×	4.2×	n/m	$47.8M
2	SPROSpero Therapeutics	2.1×	10.1×	12.8%	$64.6M
3	CRMDCorMedix	2.3×	3.7×	47.0%	$611.9M
4	ZVRAZevra Therapeutics	2.9×	10.5×	60.5%	$582.6M
5	IRWDIronwood Pharmaceuticals	3.5×	4.5×	60.1%	$571.7M
6	PRGOPERRIGO	3.7×	n/m	−37.7%	$2.2B
7	ABUSArbutus Biopharma	4.9×	5.4×	82.0%	$831M
8	NATRNatures Sunshine Products	5.2×	12.0×	6.0%	$213.8M
9	EBSEmergent BioSolutions	6.4×	n/m	−8.6%	$319.4M
10	HRMYHarmony Biosciences	6.9×	11.7×	24.0%	$2.1B
11	NRIXNurix Therapeutics	7.1×	11.0×	41.3%	$2.8B
12	INVAInnoviva	7.2×	n/m	36.9%	$1.5B
13	QTTBQ32 Bio	7.3×	n/m	n/m	$257.5M
14	PCRXPacira BioSciences	7.6×	104×	2.7%	$1.5B
15	INDVIndivior Pharmaceuticals	7.8×	12.4×	31.6%	$4.1B
16	COLLCollegium Pharmaceutical	9.4×	18.5×	19.5%	$747.5M
17	OGNOrganon	9.5×	17.9×	13.4%	$3.6B
18	LFVNLifevantage	9.6×	14.7×	3.3%	$73.4M
19	RIGLRigel Pharmaceuticals	9.7×	n/m	31.5%	$899.1M
20	BHCBausch Health Companies	10.2×	n/m	8.1%	$2.4B
21	ANIPANI Pharmaceuticals	10.5×	15.4×	15.4%	$1.7B
22	PAHCPhibro Animal Health	11.7×	15.9×	12.8%	$1.6B
23	AMPHAmphastar Pharmaceuticals	12.2×	14.8×	15.7%	$1.1B
24	AUPHAurinia Pharmaceuticals	12.3×	n/m	48.4%	$2.2B
25	BMYBristol-Myers Squibb	12.4×	13.5×	23.8%	$125.6B
26	PBHPrestige Consumer Healthcare	14.5×	13.4×	26.3%	$2.3B
27	PFEPfizer	14.5×	39.5×	21.7%	$171.2B
28	PBYIPuma Biotechnology	15.6×	21.2×	13.2%	$568.9M
29	JAZZJazz Pharmaceuticals	15.9×	14.6×	19.5%	$13.9B
30	AMRXAmneal Pharmaceuticals	18.3×	41.6×	14.6%	$6.5B
31	MRKMerck	20.4×	116×	9.6%	$358.4B
32	LQDALiquidia	21.7×	30.7×	37.4%	$3.8B
33	GILDGilead Sciences	23.4×	n/m	−8.2%	$193.5B
34	AMGNAmgen	24.6×	27.3×	30.0%	$237.5B
35	BMRNBiomarin Pharmaceutical	25.8×	151×	4.4%	$10.8B
36	BIIBBiogen	26.3×	44.4×	12.3%	$37B
37	ABBVAbbVie	27.2×	80.7×	26.2%	$504.8B
38	PTCTPTC Therapeutics	27.2×	n/m	12.5%	$5.1B
39	ACADAcadia Pharmaceuticals	29.1×	n/m	7.6%	$3.4B
40	LLYEli Lilly and	35.7×	42.7×	42.2%	$1.2T
41	XERSXeris Biopharma	54.4×	n/m	10.9%	$1.9B
42	KNSAKiniksa Pharmaceuticals International	54.6×	79.1×	11.9%	$6B
43	LGNDLigand Pharmaceuticals	57.7×	32.3×	32.6%	$6.1B
44	TGTXTG Therapeutics	62.2×	19.8×	17.1%	$8.3B
45	ALKSAlkermes plc.	69.6×	115×	7.0%	$7.3B
46	MNKDMannkind	103×	n/m	2.3%	$1B
47	ARQTArcutis Biotherapeutics	111×	142×	7.4%	$3.9B
48	PTGXProtagonist Therapeutics	140×	134×	20.7%	$9B

Not ranked: 297 with a loss over the last year, 15 with not a meaningful number, 1 with a value too high to mean anything. 51 companies whose data behind this number has a caveat are left out until it is checked.

A ranking of numbers, not a recommendation. A low multiple can be a bargain or a business in trouble: open the company to see which.