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Protagonist Therapeutics profit margin PTGX

Gross, operating and net profit as a share of revenue over the last twelve months, from 2018.

Net margin, 12 months
29.4%
Operating margin, 12 months
20.7%
Net margin on a year earlier
+4.5 pts
Peer median
8.1%

Over the twelve months to Jun 30, 2026, Protagonist Therapeutics kept 29.4% of its revenue as net profit, with an operating margin of 20.7%.

The median for 10 large drugmakers of a similar size is 8.1%.

Profit margin over time

OperatingNet

Open the interactive chart, with overlays and comparisons

Fiscal year by fiscal year

Fiscal yearNet marginOperating margin
FY2025n/an/a
FY202463.3%58.2%
FY2023n/an/a
FY2022n/an/a
FY2021n/an/a
FY2020n/an/a
FY2019n/an/a
FY2018n/an/a
FY2017n/an/a
FY2016n/an/a
FY2015n/an/a

Quarter by quarter

QuarterEndedNet margin, 12 monthsChange on a yearOperating margin
Q2 FY2629.4%+4.5 pts20.7%
Q1 FY26n/an/an/a
Q4 FY25n/an/an/a
Q3 FY2521.9%−30.8 pts9.1%
Q2 FY2524.9%−28.4 pts11.5%
Q1 FY2527.0%−24.4 pts13.1%
Q4 FY2463.3%n/a58.2%
Q3 FY2452.8%n/a46.1%
Q2 FY2453.3%n/a47.7%
Q1 FY2451.5%n/a47.2%
Q4 FY23n/an/an/a
Q3 FY23n/an/an/a

Against its peers

Companies in Drug Manufacturers - General nearest Protagonist Therapeutics' size, closest first, today.

CompanyProfit margin
PTGXProtagonist Therapeutics29.4%
CORTCorcept Therapeutics6.6%
TGTXTG Therapeutics55.2%
BMRNBiomarin Pharmaceutical2.1%
ALKSAlkermes plc.4.0%
AMRXAmneal Pharmaceuticals5.0%
LGNDLigand Pharmaceuticals67.9%
KNSAKiniksa Pharmaceuticals International9.6%
JAZZJazz Pharmaceuticals20.4%
INDVIndivior Pharmaceuticals26.7%
ARQTArcutis Biotherapeutics6.1%
Peer median8.1%

Where Protagonist Therapeutics ranks

What the profit margin tells you

Profit as a share of revenue at three levels: gross (after making the product), operating (after running the business) and net (after everything, including tax and interest).

Compare within an industry. 10% is superb for a retailer and poor for a software company.

More on Protagonist Therapeutics

Valuation data, not investment advice. Prices as of . Reported figures come from the company's filings with the SEC.