Macrogenics profit margin MGNX

Gross, operating and net profit as a share of revenue over the last twelve months, from 2012.

Net margin, 12 months: −8.7%
Operating margin, 12 months: −24.3%
Net margin on a year earlier: +15.5 pts
Peer median: 11.6%

Over the twelve months to Jun 30, 2026, Macrogenics kept −8.7% of its revenue as net profit, with an operating margin of −24.3%.

The median for 10 large drugmakers of a similar size is 11.6%.

Profit margin over time

GrossOperatingNet

Open the interactive chart, with overlays and comparisons

Fiscal year by fiscal year

Fiscal year	Net margin	Operating margin	Gross margin
FY2025	−55.6%	−59.1%	84.6%
FY2024	−44.7%	−73.7%	91.8%
FY2023	−15.4%	n/a	86.0%
FY2022	−78.8%	−79.9%	n/a
FY2021	n/a	n/a	96.6%
FY2020	n/a	n/a	100.0%
FY2019	n/a	n/a	n/a
FY2018	n/a	n/a	n/a
FY2017	−12.4%	−14.0%	n/a
FY2016	−63.7%	−65.3%	n/a
FY2015	−20.0%	−20.0%	n/a
FY2014	−80.2%	−80.2%	n/a
FY2013	−0.4%	0.6%	n/a
FY2012	13.1%	n/a	n/a

Quarter by quarter

Quarter	Ended	Net margin, 12 months	Change on a year	Operating margin
Q2 FY26	Jun 30, 2026	−8.7%	+15.5 pts	−24.3%
Q1 FY26	Mar 31, 2026	−49.6%	−13.4 pts	−49.5%
Q4 FY25	Dec 31, 2025	−55.6%	−11.0 pts	−59.1%
Q3 FY25	Sep 30, 2025	−67.6%	+1.5 pts	n/a
Q2 FY25	Jun 30, 2025	−24.2%	n/a	−56.3%
Q1 FY25	Mar 31, 2025	−36.2%	+17.4 pts	−64.6%
Q4 FY24	Dec 31, 2024	−44.7%	−29.2 pts	−73.7%
Q3 FY24	Sep 30, 2024	−69.1%	−110.2 pts	−75.8%
Q2 FY24	Jun 30, 2024	n/a	n/a	n/a
Q1 FY24	Mar 31, 2024	−53.6%	+1.6 pts	n/a
Q4 FY23	Dec 31, 2023	−15.4%	+63.4 pts	n/a
Q3 FY23	Sep 30, 2023	41.1%	n/a	−88.3%

Against its peers

Companies in Drug Manufacturers - General nearest Macrogenics' size, closest first, today.

Company	Profit margin
MGNXMacrogenics	−8.7%
NATRNatures Sunshine Products	3.7%
LFVNLifevantage	2.8%
SPROSpero Therapeutics	15.7%
ATNMActinium Pharmaceuticals	n/m
ARVNArvinas	2.9%
PBYIPuma Biotechnology	11.6%
IRWDIronwood Pharmaceuticals	33.4%
ZVRAZevra Therapeutics	42.8%
CRMDCorMedix	40.5%
COLLCollegium Pharmaceutical	5.9%
Peer median	11.6%

Where Macrogenics ranks

#47of 84Large drugmakers with the highest profit margins

What the profit margin tells you

Profit as a share of revenue at three levels: gross (after making the product), operating (after running the business) and net (after everything, including tax and interest).

Compare within an industry. 10% is superb for a retailer and poor for a software company.

More on Macrogenics

Valuation data, not investment advice. Prices as of Oct 23, 2026. Reported figures come from the company's filings with the SEC.