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Castle Biosciences profit margin CSTL

Gross, operating and net profit as a share of revenue over the last twelve months, from 2018.

Net margin, 12 months
−5.4%
Operating margin, 12 months
−9.0%
Net margin on a year earlier
−2.7 pts
Peer median
10.6%

Over the twelve months to Jun 30, 2026, Castle Biosciences kept −5.4% of its revenue as net profit, with an operating margin of −9.0% and a gross margin of 77.3%.

Five years earlier its net margin was −28.9%.

The median for 7 diagnostics and research stocks of a similar size is 10.6%.

Profit margin over time

GrossOperatingNet

Open the interactive chart, with overlays and comparisons

Fiscal year by fiscal year

Fiscal yearNet marginOperating marginGross margin
FY2025−7.0%−12.4%79.4%
FY20245.5%2.6%81.9%
FY2023−26.1%−30.9%79.5%
FY2022−49.0%−53.2%76.6%
FY2021−33.3%−42.6%83.2%
FY2020−16.4%−10.4%84.5%
FY201910.2%14.1%85.9%
FY2018−27.9%−16.8%76.8%

Quarter by quarter

QuarterEndedNet margin, 12 monthsChange on a yearOperating margin
Q2 FY26−5.4%−2.7 pts−9.0%
Q1 FY26−3.8%−2.3 pts−9.8%
Q4 FY25−7.0%−12.5 pts−12.4%
Q3 FY25−3.6%−5.5 pts−10.2%
Q2 FY25−2.7%−1.7 pts−6.7%
Q1 FY25−1.5%+10.8 pts−4.0%
Q4 FY245.5%+31.6 pts2.6%
Q3 FY241.9%+41.3 pts−0.3%
Q2 FY24−1.1%+52.0 pts−5.5%
Q1 FY24−12.3%+34.8 pts−16.7%
Q4 FY23−26.1%+22.8 pts−30.9%
Q3 FY23−39.3%+3.5 pts−44.3%

Against its peers

Companies in Medical - Diagnostics & Research nearest Castle Biosciences' size, closest first, today.

CompanyProfit margin
CSTLCastle Biosciences−5.4%
NRCNRC Health4.2%
CDNACareDx24.2%
VCYTVeracyte20.4%
BLLNBillionToOne9.5%
LNTHLantheus17.7%
CAICaris Life Sciences10.6%
BIOBio-Rad Laboratories8.6%
Peer median10.6%

Where Castle Biosciences ranks

What the profit margin tells you

Profit as a share of revenue at three levels: gross (after making the product), operating (after running the business) and net (after everything, including tax and interest).

Compare within an industry. 10% is superb for a retailer and poor for a software company.

More on Castle Biosciences

Valuation data, not investment advice. Prices as of . Reported figures come from the company's filings with the SEC.