Castle Biosciences PE ratio CSTL

Share price divided by earnings per share over the last twelve months, since 2020.

Today, Oct 23, 2026: n/m; losses over the last year
Last meaningful: 31.7×; May 2025
6-year median: 143×
6-year range: 30.4× to 499×
Peer median: 44.8×

Castle Biosciences has no meaningful PE ratio today: it lost $0.66 a share over the last twelve months, and a PE needs earnings.

It was last meaningful in May 2025, at 31.7×.

On the days it had one over the last 6 years, its median was 143×, from 30.4× in Apr 2025 to 499× in Oct 2020.

PE ratio over time

Open the interactive chart, with overlays and comparisons

Year by year

Year	End of year	Low	High
2025	31.7×	30.4×	151×
2024	134×	134×	166×
2023	n/m a value too high to mean anything
2022	n/m a value too high to mean anything
2021	n/m a value too high to mean anything
2020	470×	376×	499×

Against its peers

Companies in Medical - Diagnostics & Research nearest Castle Biosciences' size, closest first, today.

Company	PE ratio
CSTLCastle Biosciences	n/m
NRCNRC Health	87.7×
CDNACareDx	33.4×
VCYTVeracyte	34.2×
BLLNBillionToOne	166×
LNTHLantheus	24.2×
CAICaris Life Sciences	86.5×
BIOBio-Rad Laboratories	44.8×
Peer median	44.8×

What the PE ratio tells you

Share price divided by earnings per share over the last twelve months. It is the price tag on a dollar of profit: 20× means you pay $20 for $1 of yearly earnings.

Blank while earnings are negative. A very low PE can mean the market expects profits to fall, so read it with growth and the company's own history.

More on Castle Biosciences

Valuation data, not investment advice. Prices as of Oct 23, 2026. Reported figures come from the company's filings with the SEC.