| 1 | AUTLAutolus Therapeutics, Biotechnology | +292.2% | n/m | 3.5× | $409.9M |
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| 2 | CRMDCorMedix, Drug Manufacturers - General | +280.5% | 40.5% | 1.3× | $611.9M |
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| 3 | SNDXSyndax Pharmaceuticals, Drug Manufacturers - General | +222.7% | −87.5% | 4.7× | $1.2B |
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| 4 | BCYCBicycle Therapeutics, Drug Manufacturers - General | +217.4% | n/m | 4.1× | $248.5M |
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| 5 | BBIOBridgeBio Pharma, Drug Manufacturers - General | +202.4% | −97.0% | 18.8× | $13.4B |
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| 6 | IBRXImmunityBio, Biotechnology | +192.9% | n/m | 52.5× | $8.7B |
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| 7 | INSMInsmed, Biotechnology | +185.8% | −76.9% | 17.9× | $20.4B |
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| 8 | BEAMBeam Therapeutics, Biotechnology | +158.9% | −54.7% | 15.9× | $2.5B |
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| 9 | MDGLMadrigal Pharmaceuticals, Drug Manufacturers - General | +149.0% | −25.3% | 7.8× | $10B |
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| 10 | AGIOAgios Pharmaceuticals, Drug Manufacturers - General | +140.6% | n/m | 22.5× | $2.2B |
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| 11 | KYMRKymera Therapeutics, Biotechnology | +134.8% | n/m | 87.7× | $9.2B |
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| 12 | ASMBAssembly Biosciences, Drug Manufacturers - General | +125.1% | −0.1% | 5.4× | $404M |
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| 13 | TNGXTango Therapeutics, Drug Manufacturers - General | +121.5% | n/m | 73.1× | $3.9B |
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| 14 | ZVRAZevra Therapeutics, Drug Manufacturers - General | +119.4% | 42.8% | 4.3× | $582.6M |
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| 15 | PHATPhathom Pharmaceuticals, Drug Manufacturers - General | +110.2% | −41.3% | 1.9× | $464.4M |
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| 16 | TARSTarsus Pharmaceuticals, Biotechnology | +105.2% | −7.7% | 4.9× | $3B |
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| 17 | ABCLAbCellera Biologics, Drug Manufacturers - General | +101.3% | n/m | 54.8× | $3.6B |
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| 18 | URGNUroGen Pharma, Drug Manufacturers - General | +100.3% | −51.7% | 8.9× | $1.7B |
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| 19 | ALNYAlnylam Pharmaceuticals, Biotechnology | +95.1% | 16.8% | 6.2× | $30B |
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| 20 | BLLNBillionToOne, Medical - Diagnostics & Research | +90.1% | 9.5% | 12.8× | $5.1B |
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| 21 | SSIISS Innovations International, Medical - Instruments & Supplies | +89.7% | −23.7% | 8.6× | $450.9M |
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| 22 | CAICaris Life Sciences, Medical - Diagnostics & Research | +85.4% | 10.6% | 9.1× | $9B |
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| 23 | FENCFennec Pharmaceuticals, Biotechnology | +77.8% | −5.5% | 6.0× | $353.5M |
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| 24 | TVTXTravere Therapeutics, Drug Manufacturers - General | +77.1% | −7.4% | 8.0× | $4.7B |
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| 25 | ARQTArcutis Biotherapeutics, Drug Manufacturers - General | +76.1% | 6.1% | 8.5× | $3.9B |
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| 26 | TGTXTG Therapeutics, Drug Manufacturers - General | +76.1% | 55.2% | 10.4× | $8.3B |
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| 27 | BCRXBiocryst Pharmaceuticals, Biotechnology | +68.7% | −40.9% | 2.1× | $2B |
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| 28 | CARLCarlsmed, Medical - Instruments & Supplies | +65.4% | −57.4% | 6.3× | $396.7M |
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| 29 | CHRSCoherus Oncology, Biotechnology | +61.0% | n/m | 3.1× | $156M |
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| 30 | SIShoulder Innovations, Medical - Instruments & Supplies | +60.9% | −58.3% | 6.8× | $409.3M |
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| 31 | KMTSKestra Medical Technologies, Medical - Instruments & Supplies | +60.7% | n/m | 16.1× | $1.7B |
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| 32 | KNSAKiniksa Pharmaceuticals International, Drug Manufacturers - General | +58.9% | 9.6% | 7.1× | $6B |
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| 33 | AXSMAxsome Therapeutics, Drug Manufacturers - General | +56.9% | −24.7% | 9.8× | $7.6B |
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| 34 | LGNDLigand Pharmaceuticals, Drug Manufacturers - General | +54.9% | 67.9% | 20.8× | $6.1B |
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| 35 | CLOVClover Health Investments, Medical - Healthcare Plans | +54.0% | −0.7% | 1.0× | $2.4B |
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| 36 | RYTMRhythm Pharmaceuticals, Drug Manufacturers - General | +53.5% | −85.6% | 25.6× | $6.1B |
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| 37 | BBNXBeta Bionics, Medical - Instruments & Supplies | +52.5% | −61.3% | 7.2× | $862M |
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| 38 | WATWaters, Medical - Diagnostics & Research | +52.5% | 3.6% | 9.6× | $44.6B |
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| 39 | STAAStaar Surgical, Medical - Instruments & Supplies | +51.3% | 1.1% | 3.3× | $1.1B |
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| 40 | ADPTAdaptive Biotechnologies, Biotechnology | +50.1% | −20.7% | 13.2× | $4.1B |
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| 41 | LLYEli Lilly and, Drug Manufacturers - General | +49.6% | 33.5% | 15.0× | $1.2T |
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| 42 | SNDASonida Senior Living, Medical - Care Facilities | +49.4% | −23.3% | 3.1× | $1.6B |
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| 43 | SRTAStrata Critical Medical, Medical - Care Facilities | +49.3% | 15.7% | 1.6× | $412.3M |
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| 44 | OMDAOmada Health, Medical - Care Facilities | +47.6% | 1.4% | 3.7× | $1.2B |
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| 45 | MIRMMirum Pharmaceuticals, Drug Manufacturers - General | +44.0% | n/m | 8.4× | $5.2B |
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| 46 | OSCROscar Health, Medical - Healthcare Plans | +42.8% | 3.6% | 0.6× | $9.6B |
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| 47 | HTFLHeartflow, Medical - Instruments & Supplies | +42.8% | −55.8% | 23.3× | $4.9B |
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| 48 | GHGuardant Health, Medical - Diagnostics & Research | +42.7% | −38.3% | 19.2× | $22.7B |
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| 49 | GKOSGLAUKOS, Medical - Instruments & Supplies | +41.5% | −30.7% | 17.2× | $10.6B |
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| 50 | HALOHalozyme Therapeutics, Biotechnology | +41.2% | 24.9% | 8.6× | $14.3B |
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| 51 | STIMNeuronetics, Medical - Instruments & Supplies | +39.6% | −19.6% | 1.0× | $160.8M |
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| 52 | ESTAEstablishment Labs, Medical - Instruments & Supplies | +38.6% | −15.8% | 7.7× | $1.9B |
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| 53 | STLNStarling Oncology, Medical - Care Facilities | +38.4% | −6.2% | 1.2× | $683.9M |
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| 54 | PNTGPennant, Medical - Care Facilities | +37.9% | 2.9% | 1.3× | $1.5B |
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| 55 | NTRANatera, Medical - Diagnostics & Research | +37.8% | −7.1% | 21.5× | $58.2B |
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| 56 | ALHCAlignment Healthcare, Medical - Healthcare Plans | +37.2% | 0.9% | 0.4× | $1.7B |
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| 57 | XERSXeris Biopharma, Drug Manufacturers - General | +36.3% | −5.1% | 5.5× | $1.9B |
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| 58 | DCTHDelcath Systems, Medical - Instruments & Supplies | +35.8% | 0.6% | 5.2× | $500.4M |
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| 59 | PTGXProtagonist Therapeutics, Drug Manufacturers - General | +34.8% | 29.4% | 31.8× | $9B |
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| 60 | IOVAIovance Biotherapeutics, Biotechnology | +34.5% | −89.1% | 19.6× | $6.4B |
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| 61 | BDSXBiodesix, Medical - Diagnostics & Research | +34.5% | −27.0% | 2.2× | $223.5M |
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| 62 | NBIXNeurocrine Biosciences, Biotechnology | +34.4% | 20.9% | 4.3× | $14.5B |
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| 63 | CDNACareDx, Medical - Diagnostics & Research | +34.4% | 24.2% | 7.8× | $3.6B |
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| 64 | ONCBeOne Medicines, Biotechnology | +34.3% | 10.7% | 7.0× | $42.9B |
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| 65 | COSMCosmos Health, Medical - Distribution | +33.8% | −33.1% | 0.4× | $26.3M |
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| 66 | GOSSGossamer Bio, Drug Manufacturers - General | +32.4% | n/m | 1.1× | $58.7M |
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| 67 | CBLLCeribell, Medical - Devices | +31.7% | −64.7% | 10.2× | $1B |
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| 68 | ANIPANI Pharmaceuticals, Drug Manufacturers - General | +30.9% | 11.1% | 1.7× | $1.7B |
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| 69 | TFXTeleflex, Medical - Instruments & Supplies | +30.7% | −45.8% | 2.6× | $5.8B |
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| 70 | AGENAgenus, Biotechnology | +30.5% | 69.3% | 2.1× | $285M |
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| 71 | MNKDMannkind, Drug Manufacturers - General | +30.5% | −11.1% | 2.6× | $1B |
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| 72 | PLXProtalix BioTherapeutics, Biotechnology | +30.1% | 23.5% | 2.5× | $205.5M |
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| 73 | PODDInsulet, Medical - Instruments & Supplies | +29.4% | 12.3% | 3.4× | $10.3B |
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| 74 | BFLYButterfly Network, Medical - Devices | +28.1% | −66.7% | 16.1× | $1.8B |
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| 75 | HIMSHims & Hers Health, Medical - Care Facilities | +28.0% | −5.5% | 2.5× | $6.5B |
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| 76 | INCYIncyte, Biotechnology | +26.9% | 27.7% | 4.0× | $23.5B |
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| 77 | BTSGBrightSpring Health Services, Medical - Care Facilities | +26.4% | 2.5% | 0.8× | $11.9B |
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| 78 | IVVDInvivyd, Biotechnology | +26.3% | n/m | 3.1× | $180.8M |
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| 79 | IRWDIronwood Pharmaceuticals, Drug Manufacturers - General | +26.2% | 33.4% | 1.5× | $571.7M |
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| 80 | TMDXTransMedics, Medical - Devices | +25.8% | 22.7% | 3.7× | $2.5B |
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| 81 | APYXApyx Medical, Medical - Instruments & Supplies | +25.6% | −14.8% | 1.7× | $99.8M |
|---|
| 82 | IRTCiRhythm, Medical - Instruments & Supplies | +25.6% | −1.7% | 4.8× | $4B |
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| 83 | WGSGeneDx, Medical - Care Facilities | +25.4% | −23.4% | 3.7× | $1.7B |
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| 84 | VMDViemed Healthcare, Medical - Care Facilities | +25.2% | 4.8% | 1.2× | $373.3M |
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| 85 | SUPNSupernus Pharmaceuticals, Drug Manufacturers - General | +24.9% | −13.2% | 2.8× | $2.4B |
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| 86 | MEDPMedpace, Medical - Diagnostics & Research | +24.7% | 17.7% | 6.7× | $18.7B |
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| 87 | GERNGeron, Drug Manufacturers - General | +24.4% | −33.1% | 3.5× | $719.6M |
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| 88 | HRMYHarmony Biosciences, Drug Manufacturers - General | +24.3% | 18.9% | 2.2× | $2.1B |
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| 89 | PRVAPrivia Health, Medical - Care Facilities | +24.1% | 1.2% | 1.2× | $2.9B |
|---|
| 90 | AXGNAxogen, Medical - Devices | +23.6% | −13.4% | 8.1× | $2B |
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| 91 | GRALGRAIL, Medical - Diagnostics & Research | +23.1% | n/m | 35.8× | $5.9B |
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| 92 | VCELVericel, Biotechnology | +23.0% | 7.9% | 7.1× | $2.2B |
|---|
| 93 | PRCTPROCEPT BioRobotics, Medical - Instruments & Supplies | +22.7% | −32.5% | 3.4× | $1.1B |
|---|
| 94 | KRYSKrystal Biotech, Biotechnology | +22.6% | 54.8% | 20.9× | $9.2B |
|---|
| 95 | AQSTAquestive Therapeutics, Drug Manufacturers - General | +22.6% | n/m | 9.3× | $502M |
|---|
| 96 | QTRXQuanterix, Medical - Diagnostics & Research | +22.0% | −80.2% | 0.9× | $135.3M |
|---|
| 97 | HROWHarrow, Drug Manufacturers - General | +21.1% | −13.5% | 3.9× | $1.1B |
|---|
| 98 | IMCRImmunocore, Biotechnology | +21.0% | −4.2% | 3.7× | $1.6B |
|---|
| 99 | DERMJourney Medical, Drug Manufacturers - General | +20.9% | −9.0% | 2.1× | $141.7M |
|---|
| 100 | XGNExagen, Medical - Diagnostics & Research | +20.8% | −26.6% | 2.5× | $176.1M |
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