SuperworthSpyre Therapeutics market cap SYRE
Share price times shares outstanding: what the whole company sells for, since 2016.
- Today, Oct 23, 2026
- $8B
- Highest close in our data
- $9.4B
- Aug 2026
Spyre Therapeutics is worth $8B at the close on Oct 23, 2026, at $90.33 a share.
That is up 464% over the last year and up 2118% over five years.
Its highest close in our data was $9.4B in Aug 2026.
Market cap over time
Year by year
| Year | End of year | Low | High | Change |
|---|---|---|---|---|
| 2026 so far | $8B | $2.4B | $9.4B | +212% |
| 2025 | $2.6B | $736.6M | $2.6B | +110% |
| 2024 | $1.2B | $86.6M | $2B | +1297% |
| 2023 | $87.1M | $8.4M | $87.1M | +215% |
| 2022 | $27.7M | $20.9M | $224.4M | −88% |
| 2021 | $234.3M | $183.5M | $402.3M | −38% |
| 2020 | $377.3M | $116.1M | $468.2M | +65% |
| 2019 | $229M | $178.3M | $257.9M | +25% |
| 2018 | $183.8M | $90.7M | $240.4M | +104% |
| 2017 | $90M | $43.7M | $104M | +54% |
| 2016 | $58.4M | $56.5M | $103.4M | n/a |
Against its peers
Companies in Drug Manufacturers - General nearest Spyre Therapeutics' size, closest first, today.
| Company | Market cap |
|---|---|
| SYRESpyre Therapeutics | $8B |
| TGTXTG Therapeutics | $8.3B |
| ALKSAlkermes plc. | $7.3B |
| PTGXProtagonist Therapeutics | $9B |
| CORTCorcept Therapeutics | $9.3B |
| AMRXAmneal Pharmaceuticals | $6.5B |
| LGNDLigand Pharmaceuticals | $6.1B |
| KNSAKiniksa Pharmaceuticals International | $6B |
| BMRNBiomarin Pharmaceutical | $10.8B |
| JAZZJazz Pharmaceuticals | $13.9B |
| INDVIndivior Pharmaceuticals | $4.1B |
| Peer median | $7.8B |
What the market cap tells you
Share price times shares outstanding: what the whole company sells for today.
Size, not quality. Large caps move slower and are covered more. That is all it tells you.
More on Spyre Therapeutics
Valuation data, not investment advice. Prices as of . Reported figures come from the company's filings with the SEC.