Denali Therapeutics DNLI

Biotechnology, Healthcare

$18.41

−1.34%

Market cap: $2.9B
PE: n/m; a loss over the last year
Forward PE: n/m; not a meaningful number
Price to sales: n/m; one or more of the four quarters through 2026-06-30 missing
EV/EBIT: n/m; a loss over the last year
Revenue, 12 months: n/m; one or more of the four quarters through 2026-06-30 missing
Net margin: n/m; one or more of the four quarters through 2026-06-30 missing
Free cash flow yield: −14.9%

Denali Therapeutics' trailing earnings are negative, so it has no PE.

Charts

Financials

Income statement for DNLI, by quarter
Income statement	Q3 FY23	Q4 FY23	Q1 FY24	Q2 FY24	Q3 FY24	Q4 FY24	Q1 FY25	Q2 FY25	Q3 FY25	Q4 FY25	Q1 FY26	Q2 FY26
	$1.3M−64%	$0	$0	$0	$0	$0	n/a	$0	n/a	n/a	n/a	$3.6M
Cost of revenue	n/a	n/a	n/a	n/a	n/a	n/a	n/a	$0	n/a	n/a	n/a	$93K
Gross profit	n/a	n/a	n/a	n/a	n/a	n/a	n/a	$0	n/a	n/a	n/a	$3.5M
R&D	$89.7M+2%	$107.8M+17%	$107M−17%	$91.4M−6%	$98.2M+10%	$99.8M−7%	$116.2M+9%	$102.7M+12%	$102M+4%	$97.9M−2%	$103.8M−11%	$97M−6%
SG&A	$25.3M+9%	$24.8M+5%	$25.2M−7%	$25.2M−4%	$24.9M−2%	$30.1M+21%	$29.4M+16%	$32.3M+28%	$35.5M+42%	$39.5M+31%	$33.5M+14%	$36.3M+12%
	−$113.8M+6%	−$132.6M+26%	−$117.7M−3%	−$116.6M	−$123.2M+8%	−$129.8M−2%	−$145.6M+24%	−$135M+16%	−$137.4M+12%	−$137.4M+6%	−$137.4M−6%	−$130.5M−3%
Pre-tax income	−$99.4M−4%	−$119.4M+21%	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
	$0	$30K	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Net income	−$99.4M−4%	−$119.5M+21%	−$101.8M−7%	−$99M	−$107.2M+8%	−$114.8M−4%	−$133M+31%	−$124.1M+25%	−$126.9M+18%	−$128.5M+12%	−$128.4M−3%	−$127.6M+3%
	−$0.72−14%	−$0.86+16%	−$0.68−15%	−$0.59	−$0.63−13%	−$0.67−22%	−$0.78+15%	−$0.72+22%	−$0.74+18%	−$0.73+9%	−$0.69−12%	−$0.68−6%
	137.6M+12%	138.2M+4%	149.4M+9%	168.8M+20%	169.5M+23%	170.1M+23%	171.2M+15%	171.4M+2%	172.4M+2%	175.5M+3%	186.6M+9%	187.3M+9%

Revenue: Q1 FY17: 6 months less the 3 months printed beside them.

Gross profit: Q2 FY25 and Q2 FY26: not printed by the filing, worked out from its own lines.

EPS, diluted: 8 periods, Q4 FY17 to Q4 FY25: quarter's net income to common over its shares, to the cent.

Diluted shares: 6 periods, Q4 FY17 to Q4 FY25: a loss quarter: its basic count, share-days: the 12-month average less the 9-month, weighted by days. Q4 FY18: share-days: the 12-month average less the 9-month, weighted by days. Q4 FY20: the earlier year to date counted no dilution: the quarter's basic count plus the later year to date's dilution.

From each company's 10-Q and 10-K filings, the newest version of each figure. Quarters are as filed (a fourth quarter is the year less its first nine months), fiscal years as the 10-K prints them, restated where a later 10-K restated them, and balance sheet lines as of the period's end. A quarter whose 10-Q isn't filed yet is from the company's results release. Growth is on the same period a year earlier. A dash is a period with no figure for the line: the filing doesn't print it, or it hasn't been read yet.

Peers

Companies in Biotechnology nearest Denali Therapeutics' size, closest first.

Company	Market cap	PE	Its 10y median PE	Fwd PE	P/S	Revenue growth	Net margin
DNLIDenali Therapeutics	$2.9B	n/m	180×	n/m	n/m	n/m	n/m
ADMAAdma Biologics	$2.4B	15.3×	21.5×	n/m	4.7×	+8%	33.0%
VCELVericel	$2.2B	92.5×	158×	n/m	7.1×	+23%	7.9%
KRYSKrystal Biotech	$9.2B	39.0×	42.7×	n/m	20.9×	+23%	54.8%
MGTXMeiraGTx	$884.6M	13.0×	18.0×	n/m	2.2×	n/m	19.9%
RGENRepligen	$10B	242×	120×	n/m	12.7×	+16%	5.3%
TECHBIO-TECHNE	$11.4B	63.1×	61.6×	n/m	9.4×	−0%	15.0%
HALOHalozyme Therapeutics	$14.3B	37.5×	21.3×	n/m	8.6×	+41%	24.9%
NBIXNeurocrine Biosciences	$14.5B	20.9×	42.8×	n/m	4.3×	+34%	20.9%
EXELExelixis	$16B	20.3×	22.8×	n/m	6.6×	+9%	35.3%
INCYIncyte	$23.5B	14.7×	36.9×	49.5×	4.0×	+27%	27.7%
Peer median	$10.7B	29.2×	39.8×	49.5×	6.8×	+23%	22.9%